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Weight Management & Metabolism

Body composition, metabolic flexibility, and the science of fat loss.

Cover image for Retatrutide (R3TA): What the Triple Agonist Research Actually Shows
Weight Management & Metabolism16 min read

Retatrutide (R3TA): What the Triple Agonist Research Actually Shows

Retatrutide is the first investigational triple agonist targeting GLP-1, GIP, and glucagon. A close read of the Phase 2 data — mechanism, weight loss, side effects, and the questions Phase 3 still has to answer.

Jun 25, 2026Read
Cover image for Insulin Sensitivity and the Pre-Diabetic Window Most People Miss
Weight Management & Metabolism13 min read

Insulin Sensitivity and the Pre-Diabetic Window Most People Miss

Fasting glucose is the last metric to change. Here is a comprehensive look at insulin sensitivity, the pre-diabetic window most people miss, and the evidence-based levers that actually move the needle.

Jun 25, 2026Read
Cover image for GLP-1 Agonists and the Question of Metabolic Flexibility
Weight Management & Metabolism11 min read

GLP-1 Agonists and the Question of Metabolic Flexibility

GLP-1 agonists reliably reduce weight and improve glucose. The harder question is what happens to underlying metabolic flexibility. Here is what the evidence supports.

Jun 11, 2026Read
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